They revealed the news on the same day as releasing the first track "Automaton" from their forthcoming album.
This marks the London Roundhouse show as their only UK headline performance of the year, so far.
The Jay Kay fronted group are also performing at a number of festivals in 2017 in Greece, South Korea, Portugal and Newquay's Boardmaster Festival.
Their return to the live stage has been welcomed by thousands fans as they announced the news on Twitter in January.
The gig will be in support of upcoming eighth studio album Automaton, due for release on March 31.
Talking about the album Jay Kay says: "The inspiration for Automaton is in recognition of the rise of artificial intelligence and technology in our world today and how we as humans are beginning to forget the more pleasant, simple and eloquent things in life."
However fans can expect to hear their classic hits including Virtual Insanity and Space Cowboy.
The band have been established for 24 years now, achieving four UK number one albums, Grammy and MTV VMAs awards and record sales of 26 million.
When do tickets go on sale?
Meanwhile a presale will take place on Wednesday February 3 at 10am.
Keep up to date with the latest news in west London via the free getwestlondon app.
You can even set it to receive push notifications for all the breaking news in your area.