Cardiff City v AFC Wimbledon
Neal Ardley makes a return to former club Cardiff City as the Dons meet the Bluebirds for the first time since forming in 2002.
AFC Wimbledon fans will have fond memories of last season’s League Cup adventure as they claimed their first ever win over MK Dons.
They beat the Buckinghamshire club 3-2 in Milton Keynes to progress to the third round, having overcome Southend on penalties at the first hurdle.
Neal Ardley’s side bowed out at the third-round stage after a battling 2-1 loss to Bristol City.
Millwall v Barnet
Barnet last faced the Lions in the 2009/10 Johnstone's Paint Trophy with the Bees recording a 2-0 triumph over the Lions thanks to goals from Jake Hyde and Ismail Yakubu.
The Bees' last Capital One Cup outing saw them handed a 5-1 defeat at Birmingham City in the first round in 2012.
Preceding the new season due to the London 2012 Olympics, Jon Nurse gave Barnet the lead after 31 minutes.
However, Marlon King levelled the scores from the penalty spot just before half time.
The Blues picked up the pace in the second half with Steven Caldwell and Darren Ambrose making it 3-1 and the scoreline had a more flattering look as Peter Lovenkrands and Wade Elliott scored in stoppage time to inflict a heavy defeat.
Barnet will be hoping for a repeat of their 2005/06 campaign where they were beaten 4-1 by Manchester United after Bees keeper Ross Flitney was sent off after 100 seconds - a decision Red Devils boss Sir Alex Ferugson criticised.
Brentford v Oxford United
The Bees last faced United in the Johnstone's Paint Trophy in the 2005/06 season. The match ended 1-1 before Oxford triumphed on penalties.
Brentford were knocked out of the second round last year by Fulham but it was their record equalling first round match at Dagenham & Redbridge that will live long in the memory banks.
Stuart Dallas gave Brentford a 2-0 lead after nine minutes. Ashley Chambers pulled a goal back before Nick Proschwitz made it 3-1.
George Porter reduced the deficit to 3-2 before Andre Boucaud levelled it up. Andre Gray looked to have won the game before Ashley Hemmings forced extra time in the final minute.
Montell Moore gave Brentford the lead again but Jamie Cureton levelled and Hemmings made it 6-5 in extra time.
But, with four minutes left, Harlee Dean headed home to take it to penalties. Jack Connors and Chambers missed and Kevin O'Connor, with what turned out to be his final kick in professional football, scored the winning spot-kick.
Wycombe v Fulham
Fulham travel to Wycombe, who they last faced in the 2006/07 season which the Chairboys won 2-1.
Jermaine Easter and Tommy Mooney scored for the Buckinghamshire side with Heidar Helguson scoring for the Whites.
Fulham put paid to Brentford last season in a rare early season victory 1-0 that saw Ross McCormack score his first for the Whites before taking it out on the hoarding behind the Griffin Park goal in frustration that ended a barren spell.
However, Derby took it out on Fulham in the next round dispatching them 5-2 after Moussa Dembele produced two neat finishes to put the Whites ahead 2-0.
Incredibly, Fulham shipped four second-half goals to deepen worry lines on then acting manager Kit Symons, who was nonetheless handed the job full time a day.
The club’s best performance over the last decade was a quarter final appearance against the mighty foe from down the road in 2004 when they lost 2-1 at home to Chelsea.
Whisper it softly, but Frank Lampard hit the winner after Elvis Hammond (remember him) had teed up Brian McBride for a leveller that proved a mere consolation in the end.
Yeovil v QPR
QPR last faced Yeovil in the 2013/14 Championship season. Rangers won 3-0 at Loftus Road thanks to a Ravel Morrison brace and a Bobby Zamora strike.
They won 1-0 at Huish Park thanks to a Charlie Austin penalty in September 2013.
Rangers and the Capital One Cup are not the best of friends.
Step up a host of lower league clubs that dispatched Hoops at the first attempt - the last being Burton Albion last season 1-0 albeit with a depleted squad that included keeper Brian Murphy, Shaun Wright-Phillips, Junior Hoilett and Adel Taarabt making his first in 16 months.
Hoilett hit the bar, but Burton’s Adam McGurk hit the back of the net in the 77th minute for the eventual League Two champions.
Before that Swindon, Rochdale and Port Vale have all relished the chance to dump the 1967 winners out of the competition.
Ties will be played in the week beginning August 10