Brentford's plans for a new 20,000-seater capacity stadium were approved by Hounslow Council's Planning Committee this evening.
Councillors voted in favour of the proposed development at Lionel Road, which would also see residential flats and a hotel built alongside the ground.
In a meeting that lasted more than four hours, the Bees were eventually given the go-ahead and the matter will now be passed to London Mayor Boris Johnson and the Communities Secretary Eric Pickles to be rubber-stamped.
Brentford chairman Cliff Crown said: "Our vision of an exciting new hub at this brownfield site has taken a significant step towards realisation with the council’s decision to approve our application.
"The support we have received from many sections of the local community and our fans throughout this process has endorsed our belief in the need for this change.
"We would also like to express appreciation to the Council Officers and Members for demonstrating their support for our plans.
"This is a once in a generation chance to create a vibrant new stadium and adds to the buzz that is going on around Brentford.
"Brentford is on the up as a destination, with new homes, retail, sports and leisure facilities which bring new jobs to the area.
"Brentford Football Club will be returning close to where it was founded in 1889.
"We are proud of our history at Griffin Park, where we have always been a good neighbour.
"In planning for our new home, we look forward to working with residents and businesses as well as our new neighbours in Chiswick and Kew, and together we can all seek to make the most of the new opportunities for the benefit of everyone."
