Police were called at 5.10am earlier today, to reports to a crash on the M40 between junction two and three on the M40 northbound.
Two people were declared dead at the scene and a further six people have been taken to hospital to be treated for their injuries.
The motorway was closed until 10.45am - it has been reopened while police attended the scene. No further information is known about those involved.
An investigation was carried out at the scene, causing traffic chaos with drivers queuing for hours to get off the stretch at junction two.
More to come as we get it