Four fire engines and 21 firefighters from Wembley Park, Park Royal and Northolt fire stations tackled the blaze for around an hour before it was fully out.
Luckily no one was injured in the incident which ripped through half of the shop roof and damaged part of the ground floor of the shop, on Wednesday (June 3) evening.
London Fire Brigade said they were called at 7.01pm and the fire was under control at 8.36pm.
Ealing Road is lined with Indian clothes shops, jewellery stores and restaurants.
The cause of the fire is under investigation.