Travelodge's first hotel in the borough, in Greenhill Way, is "off to a flying start" in the run up to half-term events at the nearby venue, according to the new manager.
London Harrow Travelodge represents a £10 million investment for third party investors and has created 20 local jobs.
"We’ve gotten off to a flying start and business on the books is looking good with half term fast approaching", said hotel manager, Joao Maldonado, "with key events at Wembley such as: the Strictly Come Dancing Live Show, the X-Factor Tour and Disney’s ‘World of Enchantment’ in Spring.
"This is great news for the local economy too, as our research shows, Travelodge customers will collectively spend, on average, £2million annually with local businesses during their stay."
Rooms at the company’s 71st London hotel feature the "bespoke, luxurious" king-size Travelodge Dreamer bed, with bedside USB charging points and a moonlighting surround.
The new modern room also includes softer LED ceiling lighting, providing a warmer ambiance, a comfort cooling system, a Samsung 32-inch TV, complimentary tea and coffee making facilities and free WIFI.
In addition all family rooms now offer individual beds for children.
Mr Maldonado added: "We are thrilled to have opened our first Travelodge hotel in Harrow town centre as there is a desperate need for good quality accommodation at a great value price.
"Our new hotel is a few minutes from the train station and just a few stops from Wembley; making it an ideal base for business and leisure customers."
The 101-room hotel also has a Bar Café offering unlimited breakfast for guests at an extra cost.
Rooms are available from £35 and can be booked here .
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