Permission has been given to build 149 homes at an old bus depot site in North Acton .
Clearview Homes will develop the new apartments in spring next year following, after Ealing Borough Council approved the project.
The land at the junction of Horn Lane and A40 Western Avenue has been has been vacant for 20 years and will be transformed into four linked buildings that are over three to nine storeys high.
The blocks will contain one, two and three-bed apartments and come with underground parking.
In late 2019, the first residents will be able to move in and benefit from the arrival of the Crossrail link at Acton Main Line station.
The Elizabeth line will provide residents with access into central London and to Heathrow airport as well as having the Central line, North Acton Underground station, nearby.
Stephen Murphy, chief executive of Clearview Homes said: “The resolution to grant planning permission is one step towards creating a significant residential development in North Acton.
"During the planning process, we carried out extensive consultations with local councillors, ward councillors, the local community and senior officials at Ealing Council to ensure our proposals would bring a landmark development to the area.
"As part of the scheme we will also be creating some discounted market rent apartments.”
Residents have previously objected to planning in the area.
In July 2016, residents were angered after a 42-storey housing development was approved by the council.
In 2015, West Acton Residents Association (WARA) chairman, Sheela Selvajothy said that Acton's skyline was "already looking like Manhattan".
The same year residents also protested over plans to build a 102 bedroom hotel at the same location, they chanted “no hotel, no flats, we want our green corridor”.
According to Clearview Homes the plans will incorporate the green corridor through its landscaping and green wall features.
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