Uxbridge Road at The Broadway in Southall has been closed between the A3005 South Road junction and the Abbotts Road junction, because of a stabbing.
The A40 is now also closed and there is queueing traffic westbound in Uxbridge at the A437 Long Lane junction, because of flooding.
Traffic is also slow throughout West London as the A3212 Grosvenor Road remains closed between Chelsea Bridge and Lupus St due to emergency gas works. Motorists are being asked to use another route.
A3220 Earls Court Road, southbound at Cromwell Road also has one lane remains blocked due to a burst water main