Residents were evacuated and homes suffered two metres of flooding after a water main burst near Euston station.
Commuters faced morning rush hour delays after the incident began just after 4am on Friday (October 27).
Around 20 firefighters rushed to the scene at the junction of Eversholt Street and Doric Way, near Euston station, and helped lead people nearby to safety.
A London Fire Brigade spokesperson said: "Around 120 metres of roadway has been flooded to a depth of around half a metre.
"Four basement properties have been flooded to a depth of around two metres and six commercial premises have also been affected.
"Crews have led two people to safety."
Fire crews remained on scene pumping water away more than six hours after the pipe first burst.
Eversholt Street road was closed between Phoenix Road and Grafton Place and motorists are advised to avoid the area.
Thames Water, which supplies the area, worked with Network Rail to return Euston station back to normal after a 16 inch pipe burst.
A Thames Water spokesperson said: "We’re sorry for the disruption in and around Euston Station this morning. This is due to a burst water main on Eversholt Street.
"We have engineers on site, and we’ve reduced the flow. We’re now working to fully stop the flow of water and will then begin to repair the pipe.
"There has been some flooding to Euston Station and we’re working with Network Rail to clear this up as quickly as possible."
There was no impact to water supply to homes in the area.
See live updates from the incident here.
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