Besieged neighbours fear a service road behind their homes is being used by drug runners, after thugs cut through a steel fence and sledgehammered a wall to get into it.
The council installed metal gates at the entrances to the wide alley, which runs behind homes in Whitton Avenue West, but the vandals just pop the locks.
Police have stepped up their efforts to protect the neighbours but many still feel threatened and some have had their homes pelted with stones.
Mike Barnes, 71, said: "Residents don't have the protection any more. It affects about 100 houses.
"A few weeks ago residents had to chase away a flytipper trying to dump televisions and mattresses.
"They shake the gate in Vernon Rise in the early hours to burst the locks and use superglue so the locks can't go back.
"We don't know what they're doing in the early hours but some people think they're using the cover to move drugs."
Some residents use it as a short cut from the Wood End Estate to Oldfield Circus but late at night it is used for more sinister purposes.
The metal fence was repaired in the past few weeks.
However, trespassers are still climbing over it to slip through the hole in the wall behind, damaging garages in the process.
Dave Dwyer, chairman of the Wood End Residents' Association said: "I can't see it being ordinary residents because of the ferocity of the way they dismantled the fence and wall. It's got to be something more illicit than just wanting to keep another route off the estate.
"What normal resident would be walking around with an angle grinder in the early hours to take the fence down?"
The service road runs from Wood End Library behind homes to the traffic lights at Greenford Road.
Residents are frightened to speak up about the intrusion as some have had their houses stoned by the trespassers.
North Greenford Safer Neighbourhood Team sergeant Adrian Tither said: "We've been increasing our patrols and our visibility in the area until the council can get the alleyway secured.
"It's possible that it's being used as a drugs run for dealing and supplying, moving it without being seen, but it could be anything.
"There isn't any evidence of drugs, only drinking, but there has to be some reason why the gates, wall and fence are being attacked."
An Ealing Homes spokesman said: "Ealing Homes has repaired the fence and the gate at Vernon Rise twice in the last two months.
Our priority now is to work with the police to identify the people responsible for this mindless vandalism."