QPR 0-1 Southampton
The new QPR management team were in despair when a 93rd minute winner from Sadio Mane ruined their debut in charge.
Mane twisted free from Nedum Onuoha at the back post to fire high and past Rob Green's left hand to herald an exodus from home fans.
Worse still, Richard Dunne looked to have picked up a knee injury in the second half that looked suspiciously like knee ligament damage.
Charlie Austin was a breathtaking save from giving Rs the win, and there was a decent showing from Adel Taarabt, Matt Phillips and sub Mauro Zarate - all recalled from the wilderness dispatched to by former boss Harry Redknapp.
Early on, Eljero Elia's turn of pace saw him steal a yard on the Rs defence, and chip past the charging Green. Fortunately, the effort went wide of the far post.
Matt Targett would have been delighted had Matt Phillips missed the back of the Saints defender's head. Both jumped for the ball, and Targett came off worse requiring seven minutes before he was gingerly stretchered off.
The away side shook off the setback when Graziano Pelle connected with a cross to thump the bar from six yards. And in seven minutes added time, Richard Dunne's desperate attempted clearance nearly removed Elia's crown jewels. It was a close run thing as to which ball would emerge first.
It took another 20 minutes before a deep cross from the recalled Matt Phillips found Joey Barton stretching for a ball at the far post he could only hook into Fraser Forster's hands.
Seconds later second retunee Steven Caulker brilliantly blocked Mane as the Saint was about to pull the trigger from the edge of the box.
Fraser Forster showed why Roy Hodgson was watching from the stands when the England international pulled off a terrific point-blank save to deny Barton's drive flicked goalwards by Charlie Austin.
Dunne came off worse in a 50-50 challenge with Mane that seemed to twist the defender's knee. He instantly signalled the bench, but it took a couple of minutes before Eduardo Vargas came on as replacement.
Mane scored, and then Rangers were cruelly denied an equaliser when a clutch of Hoops were adjudged to have impeded Forster from a cross as the ball trickled over the line.
Rangers, 4-4-2, Green; Onuoha, Dunne (Vargas 83), Caulker, Hill; Phillips, Fer, Barton, Traore (Isla 72); Taarabt (Zarate 63), Austin; subs not used: McCarthy, Isla, Kranjcar, Henry, Zamora