No less than eleven first team members have been selected for international duty with their destinations ranging all over the world, from the US to Kenya.
That will cause Jokanovic some worries as he hopes his stars come back fully fit for the Championship run-in where Fulham have eight games left to play with the play-off places at stake.
However, it is always a positive for a club to get such international recognition and with eleven first team selected for duty, the club must be doing something right.
Here's where the Fulham stars are jetting off to.
Stefan Johansen - Norway
Johansen has been called up by Norway for their World Cup qualifier against Northern Ireland at Windsor Park, so it's a nice easy one for the Norweigian.
Norway are currently second bottom of Group C having won only once, a 4-1 win over bottom side San Marino, and have lost to Germany, Czech Republic and Azerbaijan.
They play on Sunday, March 26 in a game that kicks off at 7.45pm in Belfast.
Jesse Joronen - Finland
The 24-year-old keeper is with the Finland squad as they prepare to face Turkey in their Group I World Cup qualifier in Turkey on Friday March 24.
They then have a friendly match scheduled against Austria on Tuesday March 28 which will take place in Austria, so there's a lot of travelling for Joronen in the coming week.
Finland are currently second bottom of their group too and have a single point to their name, which came courtesy of a 1-1 draw with Kosovo.
Tom Cairney and Chris Martin - Scotland
Cairney has received his first call-up for the Scotland squad and joins Martin as they prepare to face Canada in a friendly tomorrow night at Easter Road before a World Cup qualifier against Slovenia on March 26.
Both the games are in Scotland so that's a positive for Jokanovic in that there isn't too much travelling required for two of his midfield regulars, but he will still be worried his star man Cairney could pick up a knock.
Scotland are currently second bottom of Group F, which also contains England, and have four points thanks to a win over Malta and a draw with Lithuania.
Mattias Kait - Estonia
The 18-year-old has been called up by the Estonian national side for their games against Cyprus and Croatia.
The Estonians are also second bottom of Group H and have three points after they beat Gibraltar 4-0, but they were battered 8-1 by Belgium in their last game in Brussels.
Kait will have to travel to Cyprus and then to Estonia during this international break.
Tomas Kalas - Czech Republic
Kalas will be travelling to the Czech Republic and to San Marino during this international break after he was called up to the squad for their friendly and World Cup qualifier.
They play Lithuania tomorrow night in a friendly in the Mestsky Stadium before they travel to San Marino for their Group C tie.
At the moment, they sit in fourth position have taken only five points, winning just the once against Norway back in November.
Neeskens Kebano - Congo DR
Kebano has a long journey ahead of him, 4234 miles to be exact as he travels with the Congo to take on Kenya in a friendly game.
That game is due to take place on March 26 in a 1pm kick off (London time).
Michael Madl - Austria
Madl is due to play two games with Austria after he was called up by manager Marcel Koller - one friendly and one World Cup qualifier.
First up is the Group D qualifier against Moldova in Austria, and the next game is the friendly against Finland which is also due to take place in Austria.
Austria are currently in fourth place in Group D and have been disappointing so far, with only four points to their name - six off the Republic of Ireland who currently occupy the top spot.
Tim Ream - The United States
It's a long trip for Ream as he heads across the pond to team up with the US team as they play two World Cup qualifiers this week.
First up, it's a trip to San Jose for a tie against Honduras on Saturday March 25, followed by a journey to Panama as the States play another World Cup qualifier on Wednesday March 29.
Ream will be the biggest worry for Jokanovic with the amount of airmiles he'll be accumulating in the coming week.
Ragnar Sigurdsson - Iceland
Iceland face a World Cup qualifier against Kosovo on March 24 before they fly to Dublin to face the Republic of Ireland to face Martin O'Neill's side in a friendly.
They currently sit in third place in Group I on seven points, only three behind Croatia in first having won twice against Finland and Turkey, whilst they have lost to Croatia.
Ryan Sessegnon - England U19
Sessegnon has been called up to England's U19 squad as they face three European Championship elite round qualifiers.
First they face Norway tomorrow afternoon, before a game with Spain on Friday, both with 2pm kick offs.
They finish their round of games with a game against Belarus on Monday March 27 which also kicks off at 2pm.
Meanwhile, brother Steven has been called up by England U17s for their European Qualifiers.