Grant Hall is ruled out of a date with Owls, while Joel Lynch's chances are also slim after he limped out of the 1-0 win over Bristol City on Tuesday.
No Hall demands Nedum Ounuoha covers in the centre alongside Steven Caulker, leaving James Perch at right-back and Hamalainen ready to start his first Championship game.
The Finnish teenager played all but 58 minutes in the win over City. And before that came off the bench to replace Lynch in the derby triumph over Fulham on the back of a debut against Sunderland in the EFL Cup.
As a result, striker Conor Washington has no doubt the player on loan with League Two Dagenham & Redbridge last season will step up to the plate.
The forward added: "Niko was outstanding all game against Bristol, I thought.
“To be called upon at his age in the middle of a game to put in a shift like he did I thought was incredible, so hats off to him.”
The other option up head coach Jimmy Floyd Hasselbaink's sleeve is to blood Westminster born Osman Kakay, 19, at right back and shift Perch to the other side following the teenager's appearances in the EFL Cup.
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