The frontman is the leading scorer in the Championship in 2016, despite not returning for the Bees until March after two anterior cruciate ligament injuries.
The former Chelsea striker knows full well that Hogan will be the dangerman to his Rangers side in Friday's west London derby and is relishing the challenge.
The Dutchman said: “Scott Hogan is a very good player and is very mobile. He likes to play on the counter and find space behind the defenders. I think it'll be a good challenge for my centre halves and the back four.”
QPR hammered Brentford in March with Junior Hoilett, Sebastian Polter and Tjaronn Chery on the scoresheet but Hasselbaink expects it to be a different game.
He added: “We played very well that day and Junior scored a great goal but the team performance was very good.
“It'll be a different game with different players and we will see. They are playing differently as well.
“They are playing on the counter and they're dangerous like that. We'll have to look at how we enable that.”