Fulham and Brentford do battle for the seventh time since the two west London rivals returned to being in the same division as each other.
The Bees have had the better of the contests winning three and drawing one while the Whites have been successful on two occasions; only once in the league.
The league table has also been in Brentford's favour for two of the three seasons with Fulham, this time, earning the title of the pride of west London's Championship teams.
The contests have always been exciting encounters with moments of high quality following bad mistakes.
GetWestLondon takes a look back at the previous six derby days between the two sides.
Brentford 0-1 Fulham (League Cup, August 26 2014)
Fulham drew first blood in the two sides' first meeting since 1998 as they progressed in the League Cup.
Then Bees boss Mark Warburton changed his team around, giving Nick Proschwitz a start up front, but it was the Whites who claimed victory as Ross McCormack opened his account for the club.
It was Felix Magath's last win in charge of the west Londoners and he was sacked a month later after overseeing a shocking start to the league season.
Brentford 2-1 Fulham (November 21 2014)
The first league meeting between the two sides saw a dramatic late comeback give Brentford the victory as now Bees captain Harlee Dean went from villain to hero.
The defender made a bad clearance which presented Hugo Rodallega with a golden opportunity to give the Whites the lead.
However, with nine minutes left on the clock, Dean thundered the ball into the roof of the net to put Brentford back on level terms.
And, with the clock striking 90 minutes, Jota wrote himself into Brentford folklore as his shot deflected off Dan Burn into the net to give the Bees the win.
Fulham 1-4 Brentford (April 3 2015)
Brentford were in the midst of a play-off push, while the Whites were scrambling to achieve survival in the Championship.
And the Bees needed four spectacular goals to see off their west London rivals.
Stuart Dallas bagged a brace, both of them from long-range, with the second one the pick of the bunch.
McCormack pulled a goal back from the penalty spot with just over 20 minutes remaining but a Brentford late show completed the double.
Alan Judge scored a sublime free kick before Jota made it four with a sumptuous volley moments from full time.
Fulham 2-2 Brentford (December 12 2015)
Dean Smith's second match in charge of Brentford took place at Craven Cottage and it was a different encounter to the previous two.
The Bees took the lead on 18 minutes thanks to Alan Judge's penalty but James Tarkowski's own goal levelled the scores before half-time.
Moussa Dembele put Fulham into the lead on 64 minutes but just seven minutes later, Jack O'Connell found the net to level.
Jota had a goal disallowed for offside, which turned out to be a mistake by the officials, as both sides had to settle for a point.
Brentford 3-0 Fulham (April 30 2016)
A first-half demolition job gave Brentford a thumping win over their west London rivals.
Sam Saunders scored what turned out to be his last goal in red and white stripes as the Bees took a fifth minute lead.
Scott Hogan doubled the advantage just two minutes later and the game was over as a contest before half-time as the striker added his second and the Bees' third.
Dean Smith withdrew Hogan at the break because he was still working his way back to full fitness after a cruciate ligament injury, while Tom Field made an impressive debut at left back in place of Jake Bidwell.
Brentford 0-2 Fulham (November 4 (2016)
Fulham finally claimed a league victory over the Bees earlier this season as they outclassed Dean Smith's side.
The Whites missed a hatful of chances early on but took the lead when Sone Aluko scored at the second attempt.
The Bees huffed and puffed, winning 12 corners in the process, but were unable to break the visiting defence down.
And Tom Cairney rounded off a convincing win in second half stoppage time.
