The Frenchman missed both games against the Bees' west London rivals through injury last season and he is relishing the chance to play a part in one of the most important fixtures of the season.
And he admits that he dreams of scoring the winning goal in games like these because of what it means to the fans.
“I'm itching to play. I was in the stands for the home game and could feel the atmosphere. I hope I can play a big derby like this. It will be a lot of fun,” Colin said.
“You dream of scoring the winner in derby games. I just want to focus on doing a great job in the game and keep a clean sheet. If we can score it'll be an extra but performing well is the big issue.”
Colin knows that Brentford must lift themselves after their poor performance against Barnsley last weekend.
He added: “We have a big derby on Friday so we can bring back the energy and the fans with us. It will be a big game.
“It's not the best preparation. We wish we could have the three points on Saturday. We'll have to be focused on Friday.”
“If we want to do something in this league recent results are not enough. We played away at Brighton and won.
“Even if it was a difficult game, we should bring more points than this. We really are disappointed. We need to work hard and be better.”