Flemming Pedersen will be leaving his role as B Team Head Coach at Brentford to become technical director at FC Nordsjælland.
He is currently set to leave on 1 January 2017 with club legend Kevin O’Connor stepping up to a new permanent role as B Team Head Coach.
Pedersen arrived as the club's head of football philosophy before taking over the club's development squad, now B team, after Lee Carsley's departure.
Brentford's co-director of football Rasmus Ankersen said: "Flemming is a brilliant coach, and his tactical insight and deep commitment to the game have made a big impact at Brentford FC.
“We are gutted to see him leave, but we wish him all the best in FC Nordsjælland where he has got an interesting opportunity to draw the lines of a whole football department.
“At the same time, we are excited about giving Kevin O’Connor the opportunity to step up in his coaching career.
“Kevin has grown a lot as a coach over the past 12 months, and we have no doubt that he is the right man to keep improving our B Team project when Flemming leaves."
Pedersen is returning to a club he helped win two Danish Cups, one national title and then reach the Group Stage of the UEFA Champions League in 2012.