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Led by the Women's Equality Party, the Women's March London walks in solidarity with other people marching in Washington on Saturday (January 21).
A staggering crowd have already began to make their way around London before they will centre around Trafalgar Square.
Party leader, Sophie Walker, said: "This year I want to lead a party and a movement of women and men who will stand strong in the face of racism, sexism, homophobia and all other kinds of discrimination.
"We must unite to protect our rights in the face of a US administration and uncertain Brexit negotiation.
"We must protest an environment in which many minorities feel threatened.
"We must build tolerance and diversity at all levels of society."
The march, which started at midday at the US Embassy has been deemed a "peaceful" demonstration.
Organisations have urged it is a "peaceful" demonstration and people should come with an "open mind and an open heart".
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100,000 attended Women's March London
As we bring our live blog to an end, we leave you with these tweets from protesters from across the world thanking one another for showing solidarity.
'Great atmosphere' praised in London by everyone attending in Trafalgar Square
Those gathered at Trafalgsar Square have united and said the atmosphere has been spectacular.
Sam Tipton, a demonstrator, said: “Great atmosphere down at the #Womensmarch in London today. And lovely to hear Sandi Toksvig speak #bridgesnotwalls.”
Alex Macdonald added: “Colossal march in London today. Comparable to the Iraq war demos, I’d say.”
Lydia Caines said: “I’ve never been so proud to live in this city”
Ian McKellan spotted in London March crowds
Lord of the Rings and X-Men actor Ian McKellan was spotted in the crowd by one social media user who said: “Mum’s next to Ian McKellan in the protest”
80,000 people reported to have attended today's march in London
An astonishing 80,000 are said to have attended today’s march against Donald Trump’s Presidency in London alone.
Sources such as the New York Times have reported the figure, with others on Twitter.
Protesters make it to Trafalgar Square where vast crowds gather
The well known London landmark is where the rally is set to end at around 3pm.
Watch as crowds make their way to Trafalgar Square
Crowds have shown no signs of quietening as they make their way to Trafalgar Square where various speakers will deliver speeches about what this day means for them and why they have rallied women - and men - together here in central London
Sandi Toksvig takes protest selfie
Co-founders of the Women’s Equality Party Catherine Mayer and Sandi Toksvig take get into selfie formation as they march through central London.
Sandi is also expected to compere the rally in Trafalgar Square.
WEP Leader Sophie Walker leads the way
Leader of the Women’s Equality Party and former London Mayoral Candidate Sophie Walker leads the way with party banners reading: “Reject hate. Reclaim politics”
She said: “There is a temptation to respond to Donald Trump’s presidency as if this were business as usual. This is not business as usual,” says WE party leader Sophie Walker.
“This march is a show of strength in the face of racism, sexism and misogyny unleashed during the US presidential campaign and, here, the debate over Brexit.
The intolerance and divisiveness that characterised the politics of 2016 must not be allowed to poison the world for years to come.
We march to reject the rhetoric of division and hate, and the rise of xenophobia in this country and around the world. We march with all those who are marginalised and threatened by the politics of fear, standing side by side to show that this year marks the start of a new politics of inclusion and tolerance.”
West London tube stations 'jammed' as people make their way to the protest
Demonstrators recall Trump's horrific statement about 'grabbing' women
The above statement has been widely retweeted on social media site Twitter after it horrified people. Women and men alike have shared it, with one adding: “This is the reason for me being here today”.
Crowds make their way towards Pall Mall chanting parts from Jo Cox's speech
As crowds begin to make their way towards Pall Mall, protesters have been heard to chant segments from one of the late MP Jo Cox’s speech.
Yvette Cooper, the Labour MP and chair of the home affairs select committee, will be speaking in Trafalgar Square, London, at around 2pm and is in her announcement, is set to say: “We are marching because we believe what Jo Cox said that we have more in common than what divides us and because we won’t stay on the sidelines any more.”
What route is being taken?
The routes stretches over two miles from Mayfair to Trafalgar Square and started at midday.
Protesters curved around Hyde Park before moving onto Green Park, St. James’ Street and along Pall Mall.
The route then loops around Trafalgar Square before finishing at Waterloo Place at around 3pm.
Sister marches are happening in Bangor, Belfast, Cardiff, Edinburgh, Lancaster, Leeds, Liverpool, Manchester, Shipley, Southampton, St Austell or York.
There’s also the march on Washington, which the London march is in support of. A massive 200,000 people have reportedly attended.
There are also marches in India, Australia, Brazil, Canada, France and Germany.
Pixie Geldof and Alexa Chung are just two of the celebrities who are at the march today. The fashion idol Chung has already taken to Instagram as she joins demonstrators
In Pictures: Slogans take centre stage as crowds pile into London for the march
“Kick him in the assets” and “Sorry we’re all just on our periods” were just two of hundreds of banners and placards being carried by people who are demonstrating at the protest today.
Sadiq Khan set to join Women's March London
The Mayor of London, Sadiq Khan, said he will be joining the march through central London to support women’s call for equality in light of Trump’s presidency.
“As a feminist in City Hall I fully support the fight for gender equality. It’s wrong that in 2017 someone’s life chances and fundamental rights are still dependent on their gender.
In recent decades we’ve made good progress, but there is still so much more for us to do and we must redouble our efforts to make sure that as we strive for equality we do not lose all that we have achieved.
As I march today I am more determined than ever to do everything I can to ensure that all girls growing up in London have the same opportunities in life as men.”