Oxford Street has been closed in both directions after a collision on Sunday (January 7).
Motorists have been urged to find alternate routes after the incident took place at the junction of New Bond Street.
Buses serving Oxford Street are diverted and unable to serve stops between Oxford Circus and Portman Street.
A police spokesman said: "There has been a road traffic collision on Oxford Street near the junction with New Bond Street.
Latest from west London
"Both lanes on Oxford Street currently closed whilst police and medics deal with the incident."
We will be bringing you all the latest updates on this live blog.
Keep up to date with the latest news from west London via the free getwestlondon app.
You can set up your app to see news and events from your area, and receive notifications for any breaking news.
It's available to download, for free, from the App Store or Google Play for Android .
Pedestrian rushed to major trauma centre
Speaking to getwestlondon, a London Ambulance spokesperson said the pedestrian was suffered head injuries.
“We were called at 10.50am today to reports of a road traffic collision on Oxford Street.
“We sent a cycle responder and an ambulance crew to the scene, with the first of our medics arriving in under three minutes.
“We treated a woman for head injuries and took her as a priority to a major trauma centre.”
Woman rushed to hospital
Oxford Street remains closed in both directions after the earlier crash.
A woman in her 20s has been hospitalised after the collision with a bus at the junction of New Bond Street.
Her injuries are currently not thought to be life-threatening.
To read more about the incident, click here.
Police presence
The road has been closed in both directions while emergency services make the scene safe.
Traffic severely affected
Traffic is severely affected around Oxford Street after the collision.
Motorists have been urged to find alternate routes.
Collision between bus and pedestrian
A spokesman for Metropolitan Police told getwestlondon the collision in Oxford Street was between a bus and a pedestrian.
London Ambulance Service has rushed a woman in her 20s to hospital.
Her injuries are currently not thought to be life-threatening.
Oxford Street closed in both directions
A40 Oxford Street is closed in both directions after a collision on Sunday (January 7).
Buses are currently unable to serve between Oxford Circus and Portman Street and motorists have been advised to avoid the area.
The collision took place at the junction of New Bond Street.
