Fire crews responded to reports of a fire in Hounslow Road, Hanworth, on Friday (October 2) morning.
But, upon a search of the building where people reported to see smoke, no fire was found.
A London Fire Brigade (LFB) spokesman said: "People saw some smoke and called the fire brigade.
"We attended but there was no fire."
Police said they were called at 8.16am to reports of the blaze.
A spokeswoman said: "We attended and LFB attended the premises which was searched and no trace of a fire."
The junction at Hampton Road West and Uxbridge Road was partially blocked and heavy traffic was reported in the area.