Six people have died so far and dozens more are in hospital as firefighters continue to put out the inferno that ignited at a high-rise tower block in North Kensington.
While emergency services remain at the scene of the blaze at Grenfell Towe r more than 12 hours after the fire rapidly spread throughout the building, plumes of smoke continue to rise in west London.
There are a number of roads, tube lines and buses affected as fire crews, police and the ambulance service deal with the blaze.
The A40 is closed between Marylebone Road and the Northern Roundabout.
There are other local road closures, including Ladbroke Road.
Drivers are advised to avoid the area.
Queues are reported to North Kensington, Kensington, Shepherd's Bush, Notting Hill, Hammersmith, Chiswick and surrounding areas.
There is a suspended service operating on the Hammersmith & City and Circle lines. Services are not running between Hammersmith station and Edgware Road station.
Minor delays are also being reported on the rest of the Hammersmith and City Line.
Transport for London says tickets are being accepted on local buses.
Bus services are operating with delays until further notice.
The bus routes placed on diversion include 7, 23, 52, 70, 228, 295, 316, and 452.
Bus passes are being accepted in Zones 1 and 2 on London Underground.
A number of rest centres have been set up in the local area and work is under way to find emergency accommodation.
We've set up a JustGiving page in aid of those affected. To donate visit www.justgiving.com/crowdfunding/grenfell-tower-support .
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