A mammoth 22 tonnes of waste went up in flames in Transport Avenue on Tuesday (June 13) morning.
Around 20 firefighters tackled the blaze for over an hour to bring it under control.
Plumes of thick black smoke could be seen rising from behind the GSK building in Great West Road.
One Twitter user posted a picture of the blaze from a distance.
@Alex_H_Griffin tweeted: "Black smoke coming from behind GSK Hounslow."
Four fire engines from Heston, Chiswick and Ealing attended the scene.
The fire started just after 9am and was under control by 10.25am.
A spokeswoman for the London Fire Brigade said: "We were called at 9.08am this morning (Tuesday June 13) to Transport Avenue, Brentford.
"Around 22 tonnes of rubbish was gutted by the fire at a waste transfer centre.
"Four fire engines attended and 20 firefighters and officers from Heston, Chiswick and Ealing.
"It was all under control by 10.25am.”
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