Another borough pub is set to call time after it was put up for sale by agents who confirmed it could even be knocked down.
The Cowley Brick, in Chiltern View Road, Cowley, is being de-licensed and put up for sale, and its fate has been left for potential buyers to decide.
The current landlord decided to move to Liverpool for family reasons and sell up, leaving a question mark over the pub's future.
New Ballerino and Company, who are conducting the sale, said that the pub could become a residential property or even a restaurant.
A spokesman said: "The Cowley Brick is up for freehold sale for around £350,000.
"We have had quite a few people interested in it, viewings are taking place at the moment.
"It really is up to the new owner what they decide to do with it.
"It would be a shame to knock it down as it would work well as a residential property, either in its current form or as newly built flats, or even a restaurant, but it is up to the new owners, whoever they may be."
Any buyers would have to submit planning or change of use applications to Hillingdon Council for approval.
The pub is on the corner of Chiltern View Road and Whitehall Road.
It is two storeys tall and the first floor has space to accommodate four bedrooms.
Sergant Ian Meens, Hillingdon Police's licensing officer, doubts whether the site would be suitable for use as a restaurant.
He said: "It wouldn't work, there would be too many problems with parking and there's no passing trade.
"It's the first pub to bite the dust this year.
"I said there would be about six to go. "The neighbours won't be unhappy it's going, it was right on their doorstep.
"The pub was trapped really, it could-n't really have live music events because it caused problems for the neighbours.
"It was a tradesmen's pub, and the smoking ban hurt it as more people were pushed outside in the afternoons.
"It had problems with lack of parking and noise and the locals weren't warming to it."