BBC London transport correspondent Tom Edwards visited Ickenham and met with local campaigners Lottie Jones of Ruislip Against HS2, Brian Adams of Ickenham Residents' Association and Ruislip, Northwood and Pinner MP Nick Hurd .
Mr Adams told BBC News: "Everybody in Ickenham is going to suffer, 10,000 residents? All the roads will be heavily congested by thousands of HGV lorries, noise pollution, 24hour working, for 10 plus years."
HS2 Ltd said a tunnel through Ickenham was considered but: "ending the tunnel at west Ruislip offered the best solution from an environmental, construction and cost perspective.
"A new railhead will be built to the west of Ickenham that will allow large amounts of material to be removed by rail, reducing the number of required traffic movements," it said.
Mr Hurd has launched a joint campaign with Uxbridge and South Ruislip MP Sir John Randall and Beaconsfield MP Dominic Grieve calling on the Government to drop proposals for a Heathrow spur on the HS2 line.
He argues the provisional budget for the spur, almost £2billion, could be better spent elsewhere and campaigners say the Heathrow spur is the reason why HS2 will not extend the tunnel through Ickenham, because connections between the spur and the main line HS2 track could not be sited in tunnels, they would have to connect above ground.
In April, Mayor of London and the Prospective Parliamentary Candidate to retain Mr Randall's seat for the Conservatives at the next general election, Boris Johnson, labelled the spur a "ludicrous waste of money."
In his monthly HS2 update to his constituents Mr Hurd described his struggle to get a clear answer from HS2 on HGV movements in Ruislip High Street, Bury Street and Ladygate Lane as 'shambolic'.
"It is staggering to me that an organisation being trusted with so much public money could be this incompetent," he said.
When he stood down from his role as Minister for Civil Society in David Cameron's cabinet reshuffle in July, Mr Hurd told Get West London: "The current proposal [for HS2] is unacceptable.
"If we don’t get the changes we need then I will vote against it at the next stage. "