More than 400 cannabis plants with an estimated street value of £50,000 were discovered by police when they raided a house after tip-offs from concerned residents.
The haul was found by officers at a house in Edinburgh Drive, Ickenham, when they searched the property earlier this month.
Three rooms inside the house had been converted to grow cannabis, with most plants fully grown and in the process of being cut for supply. A large amount of cultivating equipment was also present. All plants have now been seized and destroyed.
The raid came after concerned residents alerted Ickenham Safer Neighbourhood Team which obtained a search warrant for the rented property.
Team member PC Andy Kirkland said: "Early intervention by the police has prevented the plants from being converted to the herbal form of cannabis and (it) did not make its way on to our streets.
"This is a prime example of the local community working alongside the local police.
"We are here to improve the quality of life of the local communities and these sort of activities will not be tolerated."
So far no arrests have been made, and police are trying to track down the suspects.
Police have also issued a list of warning signs for residents who fear a neighbouring property may be being used as a cannabis factory. They include irregular attendance at an address (often by a single occupant), windows with curtains permanently drawn, short-term renting of a property and no frost being seen on a roof at this time of year because of heat coming from the house.