Lorna Cumming-Bruce will take on the challenge on 24 April in a bid to complete the 26.2 mile course that was denied to her last year after sustaining an ankle injury.
Lorna said: "I'm more determined than ever to finish this race. I'll be doing that with a huge smile on my face if I achieve my target of £10,000.
“With depression affecting a great and growing number of us, the work the Charlie Waller Memorial Trust does is hugely and increasingly important. Every penny counts in the fight against this debilitating disease.”
Lorna's personal link with depression through family members past and present made her decide to use the race as a chance to raise awareness about the illness which affects 2.6 people in every 100, with as many as one in four suffering from some form of mental health problem in the UK each year.
With more than £7,300 already pledged to Lorna's Just Giving donation page (73%), her £10,000 target seems within reach.
Lorna is hoping to finish the race in around 4 hours, and will be one of six runners taking part in aid of CWMT this year.
The Virgin Money London Marathon starts in Greenwich Park, Blackheath, on Sunday April 24 at 10am.