A man nicknamed Mr Angry battered a care worker to death with a fire extinguisher in Acton after she asked him to turn down the volume on his TV.
Michael Meanza, 47, bludgeoned Jenny Foote, 38, over the head and face at the mental health charity-run Collette House in Acton, Ealing .
He had admitted manslaughter and denied murder on the basis he has anger issues.
But an Old Bailey jury found him guilty of murder and he was jailed for life with a minimum term of 24 years.
Judge John Bevan QC said he had no doubt Meanza would be an "ongoing danger" and said the parole board would have to think "long and hard" before considering him for release.
He highlighted Meanza's violent past, which included assaulting a hospital worker, but said it was a question for others whether the hostel had been an appropriate place for him.
Ms Foote, described by family as having a heart of gold, had been put in an "extremely vulnerable position" as the defendant had shown "signs of difficulties", he added.
As he was sent down, Meanza shouted out: "God is my judge. Put me down. Eternal damnation is yours."
Members of Ms Foote's family wept in court. They included her elderly parents and brother, the retired police officer Michael Foote.
The "ferocious and brutal" attack
In the early hours of July 7 last year, Ms Foote had gone to Meanza's room to speak to him after receiving a complaint from a neighbour about the noise from his TV, the court heard.
Meanza had been watching the 1991 psychedelic biopic The Doors starring Hollywood star Val Kilmer as the late rock star Jim Morrison.
The defendant chatted with Ms Foote in the doorway of his room for about five minutes before she returned to her office, the court heard.
After brooding for three hours, Meanza left his room, went downstairs and carried out the "ferocious and brutal" attack.
Afterwards, Meanza told police that the incident with Ms Foote was "the straw that broke the camel's back".
He told officers that care workers had interfered in his life with his girlfriend "trying to tell me how to have my relationship because of the section I am in".
Asked if he had any regrets, he smiled and said: "I have some regrets in my life but then again too few to list..."
In further interview, he explained: "I couldn't take any more. They said I can be with her and then after a while they pull us apart ... That would drive you bonkers. I snapped."
Nothing prepared Ms Foote's brother for having to break the news of his sister's murder to his elderly parents
Meanza, who had been the subject of a hospital order since the 1990s, argued that he was suffering from a "severe anger pathology" - a personality disorder which affected his ability to exercise self-control.
The court heard he had 16 previous convictions for 79 offences, mainly in the 1980s and 1990s.
They included an assault on a hospital member of staff and an assault on a female patient on a psychiatric ward after she refused to perform a sex act on him in exchange for cigarettes.
Ms Foote's brother Michael told the court that nothing prepared him for having to break the news of his sister's murder to his elderly parents - despite a police career spanning 30 years, including 10 in homicide.
He described his sister as having "a heart of gold", saying she wanted to help others less fortunate.
Mr Foote added: "In my 30 years as a police officer, investigating a number of homicides, I have never been fully prepared for a situation like this and it is tragic that someone who is working in the health care profession should be put in such a difficult position.
"It could have been anybody."
As Mr Foote described the "traumatic" impact on the close knit family, Meanza stood up in the dock to interrupt and say "I'm sorry".
In mitigation, Bernard Richmond QC said: "It would be easy to demonise Mr Meanza and label him as Mr Angry. That would be too simplistic.
"Whether Collette House was the appropriate place for a man with his difficulties is a question others will have to ask themselves.
"The reality was a woman who should not have had to deal with a man like Mr Meanza alone was in a position where she had to do just that."
Collette House in Perryn Road, Acton, is owned by mental health charity Cyrenians London and provides accommodation for a number of residents with varying mental health issues.